%0 Journal Article %T Effects of high-intensity training on muscle lactate transporters and postexercise recovery of muscle lactate and hydrogen ions in women %+ Université Montpellier 1 - UFR de Médecine (UM1 Médecine) %+ Université d'Évry-Val-d'Essonne (UEVE) %+ Università degli studi di Verona = University of Verona (UNIVR) %+ School of Human Movement and Exercise Science %+ Institute of food, Nutrition and Human health %+ Muscle et pathologies %A Thomas, Claire %A Bishop, David J. %A Edge, Johann %A Mercier, Jacques %< avec comité de lecture %@ 0363-6119 %J AJP - Regulatory, Integrative and Comparative Physiology %I American Physiological Society %V 295 %N 6 %P 1991-1998 %8 2008 %D 2008 %K buffer capacity %K monocarboxylate transporter 1 %K monocarboxylate transporter 4 %K phosphocreatine resynthesis %K females %Z Humanities and Social Sciences/Sport %Z Humanities and Social Sciences/Sport/Sport physiologyJournal articles %X The purpose of this study was to investigate the effects of high-intensity interval training (3 days/wk for 5 wk), provoking large changes in muscle lactate and pH, on changes in intracellular buffer capacity (j3min vitro), monocar- boxylate transporters (MCTs), and the decrease in muscle lactate and hydrogen ions (H+) after exercise in women. Before and after train- ing, biopsies of the vastus lateralis were obtained at rest and imme- diately after and 60 s after 45 s of exercise at 190% of maximal O2 uptake. Muscle samples were analyzed for ATP, phosphocreatine (PCr), lactate, and H+; MCT1 and MCT4 relative abundance and j3min vitro were also determined in resting muscle only. Training provoked a large decrease in postexercise muscle pH (pH 6.81). After training, there was a significant decrease in j3min vitro (-11%) and no significant change in relative abundance of MCT1 (96 + 12%) or MCT4 (120 + 21%). During the 60-s recovery after exercise, training was associated with no change in the decrease in muscle lactate, a significantly smaller decrease in muscle H+, and increased PCr resynthesis. These results suggest that increases in j3min vitro and MCT relative abundance are not linked to the degree of muscle lactate and H+ accumulation during training. Furthermore, training that is very intense may actually lead to decreases in j3min vitro. The smaller postexercise decrease in muscle H+ after training is a further novel finding and suggests that training that results in a decrease in H+ accumulation and an increase in PCr resynthesis can actually reduce the decrease in muscle H+ during the recovery from supramaximal exercise. %G English %2 https://insep.hal.science//hal-01586192/document %2 https://insep.hal.science//hal-01586192/file/Bishop%20et%20al.%20Am%20J%20Reg%20Int%20Comp%20Physiol%20295%20%286%29%20R1991%20%282008%29.pdf %L hal-01586192 %U https://insep.hal.science//hal-01586192 %~ SHS %~ INSERM %~ UNIV-MONTP1 %~ UNIV-EVRY %~ INSEP %~ UNIV-MONTPELLIER %~ UM1-UM2 %~ TEST3-HALCNRS